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Avandia News: Diabetes Drug May Up Bone Fractures Women taking the diabetes drugs Avandia, Avandamet, or Avandaryl may be more likely to fracture their bones than those using other diabetes drugs. New oral drug for type 2 diabetes shows promise The first of a new class of oral antidiabetic drugs is able to lower blood sugar (glucose) in type 2 diabetes as well as Avandia (rosiglitazone) does, but without causing weight gain, according to a report in the journal Diabetes Care.