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Prilosec News: Anti-reflux drugs safe for long-term use in kids Long-term use of proton pump inhibitors (PPIs)--drugs such as Prilosec (omeprazole) and Prevacid (lansoprazole) that are used to stop stomach acid from "refluxing" into the esophagus--appears to be safe and effective in children, according to a report in The Journal of Pediatrics. Tommy's Story "I am 71 yrs old & have Suffered from GERD for many yrs. I have been taking Prilosec 20mg since it came on the market & thank God for it.... Personal Story - Bette's Story "I have had chronic heartburn for about 10 years. Two years ago I was diagnosed with Barrett's. I am on Prilosec OTC and Zantac 300 everyday. Also I take Klonopin... Proton Pump Inhibitors Increase Risk of Hip Fracture Proton pump inhibitors (e.g. Nexium, Aciphex, Prevacid, Protonix, and Prilosec), which are taken for acid-related diseases and also by many arthritis patients trying to reduce potential gastrointestinal side effects...